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Insulin-like growth factor-1 reduces cardiac autosis through decreasing AMPK/FOXO1 signaling and Na+/K+-ATPase-Beclin-1 interaction

Introduction Insulin-like growth factor-1 (IGF-1) promotes survival and inhibits cardiac autophagy disruption. Methods Male Wistar rats were treated with IGF-1 (50 µg/kg), and 24 h after injection hearts were excised. The level of interaction between Beclin-1 and the α 1 subunit of sodium/potassiu...

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Hauptverfasser: Katarina Banjac, MIlan Obradovic, Sonja Zafirovic, Esma R. Isenovic
Format: Artigo
Sprache:Inglês
Veröffentlicht: Termedia Publishing House 2024-01-01
Schriftenreihe:Archives of Medical Science
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Online-Zugang:https://www.archivesofmedicalscience.com/Insulin-like-growth-factor-1-reduces-cardiac-autosis-through-decreasing-AMPK-FOXO1,177618,0,2.html
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