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An updated comparison of microarray and RNA-seq for concentration response transcriptomic study: case studies with two cannabinoids, cannabichromene and cannabinol

Abstract Background Transcriptomic benchmark concentration (BMC) modeling provides quantitative toxicogenomic information that is increasingly being used in regulatory risk assessment of data poor chemicals. Over the past decade, RNA sequencing (RNA-seq) is gradually replacing microarray as the majo...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Xiugong Gao, Miranda R. Yourick, Kayla Campasino, Yang Zhao, Estatira Sepehr, Cory Vaught, Robert L. Sprando, Jeffrey J. Yourick
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-04-01
Schriftenreihe:BMC Genomics
Schlagworte:
Microarray
RNA-seq
Toxicogenomics
Concentration response
BMC modeling
In vitro
Online-Zugang:https://doi.org/10.1186/s12864-025-11548-3
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