Single-cell profiling reveals distinct populations of tumor-associated macrophages and metastatic tumor cells in breast cancer brain metastasis

Abstract Breast cancer brain metastasis (BCBM) is a major cause of breast cancer-related mortality, but the molecular mechanisms underlying its progression remain poorly understood. Here, we profiled the tumor immune microenvironment of BCBM at single-cell resolution and identified candidate regulat...

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Detalhes bibliográficos

Principais autores:	Haoyuan Shi, Jiaxin Chen, Zisheng Wu, Dong-Xu Liu, Jinmei Zhou, Xuexue Wu, Ailing Yang, Shanhu Li, Yanhong Tai, Zefei Jiang, Zhiyuan Hu, Mingshan Zhang, Xiaojie Xu, Lu Pan, Tao Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2026-04-01
coleção:	Cell Death and Disease
Acesso em linha:	https://doi.org/10.1038/s41419-026-08807-w
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