Isolation and light chain shuffling of a Plasmodium falciparum AMA1-specific human monoclonal antibody with growth inhibitory activity

Abstract Background Plasmodium falciparum, the parasite causing malaria, affects populations in many endemic countries threatening mainly individuals with low malaria immunity, especially children. Despite the approval of the first malaria vaccine Mosquirix™ and very promising data using cryopreserv...

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Detalhes bibliográficos

Principais autores:	Melanie Seidel-Greven, Otchere Addai-Mensah, Holger Spiegel, Gwladys Nina Chiegoua Dipah, Stefan Schmitz, Gudrun Breuer, Margaret Frempong, Andreas Reimann, Torsten Klockenbring, Rainer Fischer, Stefan Barth, Rolf Fendel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-01-01
coleção:	Malaria Journal
Assuntos:	Malaria Plasmodium falciparum Apical membrane antigen 1 Human monoclonal antibodies Parasite growth inhibition Phage display
Acesso em linha:	https://doi.org/10.1186/s12936-020-03548-3
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