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Desmin interacts with STIM1 and coordinates Ca2+ signaling in skeletal muscle

Stromal interaction molecule 1 (STIM1), the sarcoplasmic reticulum (SR) transmembrane protein, activates store-operated Ca2+ entry (SOCE) in skeletal muscle and, thereby, coordinates Ca2+ homeostasis, Ca2+-dependent gene expression, and contractility. STIM1 occupies space in the junctional SR membra...

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Principais autores: Hengtao Zhang, Victoria Graham Bryson, Chaojian Wang, TianYu Li, Jaclyn P. Kerr, Rebecca Wilson, Deborah M. Muoio, Robert J. Bloch, Christopher Ward, Paul B. Rosenberg
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical investigation 2021-09-01
Serier:JCI Insight
Fag:
Muscle biology
Online adgang:https://doi.org/10.1172/jci.insight.143472
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