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Safety and efficacy of glibenclamide on functional outcomes in ischemic and hemorrhagic stroke: a systematic review and meta-analysis of randomized clinical trials

BackgroundSecondary brain injuries, including delayed cerebral ischemia, neuroinflammation, and stroke induced cerebral edema can occur following both ischemic and hemorrhagic strokes, contributing to a negative impact on clinical outcomes. Glibenclamide, a sulfonylurea antidiabetic medication, has...

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Библиографические подробности
Главные авторы: Ola Bin Shilash, Hussam Alhathlol, Rana Alduhaysh, Razan Almufarriji, Mohammed Bafaquh
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2025-06-01
Серии:Frontiers in Neurology
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Online-ссылка:https://www.frontiersin.org/articles/10.3389/fneur.2025.1609101/full
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