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M2 Macrophages Promote PDGFRβ+ Pericytes Migration After Spinal Cord Injury in Mice via PDGFB/PDGFRβ Pathway

Platelet derived growth factor receptor β positive (PDGFRβ+) pericytes form fibrotic scar, which prevents axonal regeneration after spinal cord injury (SCI). However, the mechanism by which PDGFRβ+ pericytes migrate to the injury core is unclear. Here, we investigated the effect and mechanism of mac...

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Autores principales: Ziyu Li, Meige Zheng, Shuisheng Yu, Fei Yao, Yang Luo, Yanchang Liu, Dasheng Tian, Li Cheng, Juehua Jing
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021-04-01
Colección:Frontiers in Pharmacology
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Acceso en línea:https://www.frontiersin.org/articles/10.3389/fphar.2021.670813/full
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