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Triple combination antiviral drug (TCAD) composed of amantadine, oseltamivir, and ribavirin impedes the selection of drug-resistant influenza A virus.

Widespread resistance among circulating influenza A strains to at least one of the anti-influenza drugs is a major public health concern. A triple combination antiviral drug (TCAD) regimen comprised of amantadine, oseltamivir, and ribavirin has been shown to have synergistic and broad spectrum activ...

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Auteurs principaux: Justin D Hoopes, Elizabeth M Driebe, Erin Kelley, David M Engelthaler, Paul S Keim, Alan S Perelson, Libin Rong, Gregory T Went, Jack T Nguyen
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2011-01-01
Collection:PLoS ONE
Accès en ligne:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0029778&type=printable
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