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Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly

Human immunodeficiency virus type-1 (HIV-1) encodes a polypeptide called Gag that is able to form virus-like particles (VLPs) in vitro in the absence of any cellular or viral constituents. During the late phase of the HIV-1 infection, Gag polyproteins are transported to the plasma membrane (PM) for...

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Autors principals: Ruba H Ghanam, Alexandra B Samal, Timothy F Fernandez, Jamil S Saad
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2012-02-01
Col·lecció:Frontiers in Microbiology
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Accés en línia:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00055/full
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