A P5-ATPase, TgFLP12, diverging from plant chloroplast lipid transporters mediates apicoplast fatty export in Toxoplasma

Abstract Toxoplasma gondii, an apicomplexan parasite and agent of the human disease toxoplasmosis, possesses a non-photosynthetic relic plastid, named the apicoplast. Thought to be evolved from a red algal plastid, the apicoplast houses major metabolic pathways, such as heme, isoprenoid and lipid sy...

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Autori principali: Christophe-Sébastien Arnold, Anna-Maria Alazzi, Serena Shunmugam, Jan Janouškovec, Laurence Berry, Sarah Charital, Thierry Gautier, Samuel Duley, Delphine Jublot, Catherine Lemaire-Vieille, Marie-France Cesbron-Delauw, Pierre Cavailles, Jérôme Govin, Nicholas J. Katris, Yoshiki Yamaryo-Botté, Cyrille Y. Botté
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-07-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-025-61155-9
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