Dapagliflozin treatment is associated with a reduction of epicardial adipose tissue thickness and epicardial glucose uptake in human type 2 diabetes

Abstract Objective We recently demonstrated that treatment with sodium-glucose cotransporter-2 inhibitors (SGLT-2i) leads to an increase in myocardial flow reserve in patients with type 2 diabetes (T2D) with stable coronary artery disease (CAD). The mechanism by which this occurs is, however, unclea...

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Autori principali:	Francesca Cinti, Lucia Leccisotti, Gian Pio Sorice, Umberto Capece, Domenico D’Amario, Margherita Lorusso, Shawn Gugliandolo, Cassandra Morciano, Andrea Guarneri, Maria Angela Guzzardi, Teresa Mezza, Amedeo Capotosti, Luca Indovina, Pietro Manuel Ferraro, Patricia Iozzo, Filippo Crea, Alessandro Giordano, Andrea Giaccari
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2023-12-01
Serie:	Cardiovascular Diabetology
Soggetti:	Diabetes Metabolism Epicardial adipose tissue PET SGLT-2i Microvascular dysfunction
Accesso online:	https://doi.org/10.1186/s12933-023-02091-0
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