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GPT2 Is Induced by Hypoxia-Inducible Factor (HIF)-2 and Promotes Glioblastoma Growth

Hypoxia-inducible factor (HIF) directly activates the transcription of metabolic enzymes in response to hypoxia to reprogram cellular metabolism required for tumor cell proliferation. Through analyzing glutamate-linked aminotransferases, we here identified glutamate pyruvate transaminase 2 (<i>GPT2<...

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Príomhchruthaitheoirí: Bo Zhang, Yan Chen, Lei Bao, Weibo Luo
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: MDPI AG 2022-08-01
Sraith:Cells
Ábhair:
Rochtain ar líne:https://www.mdpi.com/2073-4409/11/16/2597
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