New Compounds with Bioisosteric Replacement of Classic Choline Kinase Inhibitors Show Potent Antiplasmodial Activity

In the fight against Malaria, new strategies need to be developed to avoid resistance of the parasite to pharmaceutics and other prevention barriers. Recently, a Host Directed Therapy approach based on the suppression of the starting materials uptake from the host by the parasite has provided excell...

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Hlavní autoři:	Francisco José Aguilar-Troyano, Archimede Torretta, Gianluca Rubbini, Alberto Fasiolo, Pilar María Luque-Navarro, María Paz Carrasco-Jimenez, Guiomar Pérez-Moreno, Cristina Bosch-Navarrete, Dolores González-Pacanowska, Emilio Parisini, Luisa Carlota Lopez-Cara
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-11-01
Edice:	Pharmaceutics
Témata:	antimalarial drug choline kinase inhibition
On-line přístup:	https://www.mdpi.com/1999-4923/13/11/1842
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