Assessing mutation accumulation in DNA repair-deficient Listeria monocytogenes: implications for cgMLST cluster thresholds in outbreak analysis

BackgroundListeria (L.) monocytogenes is primarily transmitted via contaminated food and can cause listeriosis, an infection often associated with sepsis and meningitis in at-risk individuals. Accurate outbreak detection relies on whole genome sequencing (WGS) and core genome multilocus sequence typ...

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Auteurs principaux:	Astrid Füszl, Ariane Pietzka, Patrick Hyden, Tobias Mösenbacher, Anna Stöger, Marion Blaschitz, Silke Stadlbauer, Petra Hasenberger, Stefanie Schindler, Florian Heger, Sonja Pleininger, Alexander Indra
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2025-02-01
Collection:	Frontiers in Cellular and Infection Microbiology
Sujets:	Listeria monocytogenes listeriosis mutation rate core genome multilocus sequence typing allele threshold outbreak detection
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fcimb.2025.1530851/full
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