Lactate and lactylation in cancer: drivers of immune suppression and microenvironmental reprogramming
Abstract Lactate, a key metabolite of the Warburg effect, plays a central role in shaping multiple hallmarks of cancer. Through lactate shuttling and engagement with specific receptors, it activates downstream signaling pathways that remodel the tumor microenvironment (TME) and facilitate tumor prog...
I tiakina i:
| Ngā kaituhi matua: | , |
|---|---|
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
BMC
2025-10-01
|
| Rangatū: | Experimental Hematology & Oncology |
| Ngā marau: | |
| Urunga tuihono: | https://doi.org/10.1186/s40164-025-00719-3 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
|