Glycolysis in the tumor microenvironment shapes dendritic cell function and antitumor immunity

Dendritic cells (DCs) are central orchestrators of antitumor immunity, but their functions are markedly curtailed by glycolysis-dominated metabolic constraints in the tumor microenvironment (TME). This review focuses on two interconnected dimensions: tumor-derived metabolic stressors that suppress D...

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Detalhes bibliográficos

Principais autores:	Bo Zhang, Linlin Zhao, Huzi Li, Na Wang, Xuerui Wang, Lihan Shang, Bingsheng Sun, Fanming Kong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-02-01
coleção:	Frontiers in Immunology
Assuntos:	dendritic cells glycolysis immune tolerance immunotherapy metabolic reprogramming tumor microenvironment
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1744671/full
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