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Evidence of innate training in bovine γδ T cells following subcutaneous BCG administration

The Bacillus Calmette Guerin (BCG) vaccine has been shown to induce non-specific protection against diseases other than tuberculosis in vaccinated individuals, attributed to the induction of trained immunity. We have previously demonstrated that BCG administration induces innate immune training in m...

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Principais autores: Beulah Esther Rani Samuel, Fabian E. Diaz, Teresia W. Maina, Ryan J. Corbett, Christopher K. Tuggle, Jodi L. McGill
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-07-01
Serier:Frontiers in Immunology
Fag:
trained immunity
bovine γδ T cells
chromatin accessibility
BCG vaccine
epigenetic reprogramming
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1423843/full
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