Resveratrol-Enhanced Human Neural Stem Cell-Derived Exosomes Mitigate MPP+-Induced Neurotoxicity Through Activation of AMPK and Nrf2 Pathways and Inhibition of the NLRP3 Inflammasome in SH-SY5Y Cells

Parkinson’s disease (PD) is a progressive neurodegenerative disorder primarily characterized by the loss of dopaminergic neurons in the substantia nigra. Mitochondrial dysfunction, oxidative stress, and neuroinflammation are recognized as critical pathological mechanisms driving neurodegeneration in...

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Principais autores:	Ming-Chang Chiang, Yu-Ping Yang, Christopher J. B. Nicol, Tairui Chiang, Chiahui Yen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-02-01
Colecção:	Life
Assuntos:	resveratrol AMPK exosomes MPP<sup>+</sup> neuroprotection
Acesso em linha:	https://www.mdpi.com/2075-1729/15/2/294
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