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Combination of oligo-fractionated irradiation with nivolumab can induce immune modulation in gastric cancer

Background Tumor-associated antigen (TAA)-specific CD8(+) T cells are essential for nivolumab therapy, and irradiation has been reported to have the potential to generate and activate TAA-specific CD8(+) T cells. However, mechanistic insights of T-cell response during combinatorial immunotherapy usi...

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Автори: Ajay Goel, Yuya Yoshimoto, Yate-Ching Yuan, Takashi Ogata, Hiroyuki Katoh, Yoshiyuki Suzuki, Fumiaki Takahashi, Takashi Oshima, Daisaku Yoshida, Alessandra Nardin, Michael Fehlings, Kosaku Mimura, Phuong H D Nguyen, Souvick Roy, Hassen Kared, Shotaro Nakajima, Hisashi Sato, Nozomu Machida, Takanobu Yamada, Yohei Watanabe, Tomoaki Tamaki, Hirohito Fujikawa, Yasuhiro Inokuchi, Suguru Hayase, Hiroyuki Hanayama, Zenichiro Saze, Koji Kono
Формат: Artigo
Мова:Inglês
Опубліковано: BMJ Publishing Group 2024-01-01
Серія:Journal for ImmunoTherapy of Cancer
Онлайн доступ:https://jitc.bmj.com/content/12/1/e008385.full
Теги: Додати тег
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