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In Vitro Genotoxicity Evaluation of PAHs in Mixtures Using Experimental Design

Settled dusts are sinks for environmental pollutants, including Polycyclic Aromatic Hydrocarbons (PAHs) that are ubiquitous, persistent, and carcinogenic. To assess their toxicity in mixtures, Toxic Equivalent Factors (TEFs) are routinely used and based on the hypothesis of additive effects, althoug...

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Principais autores: Rebecca Castel, Virginie Tassistro, Magalie Claeys-Bruno, Laure Malleret, Thierry Orsière
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-05-01
coleção:Toxics
Assuntos:
genotoxic equivalent factors
design of experiment
interaction effects
mixture hazard
comet assay
micronucleus
Acesso em linha:https://www.mdpi.com/2305-6304/11/5/470
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