4,7-Disubstituted 7<i>H</i>-Pyrrolo[2,3-d]pyrimidines and Their Analogs as Antiviral Agents against Zika Virus
Discovery of compound <b>1</b> as a Zika virus (ZIKV) inhibitor has prompted us to investigate its 7<i>H</i>-pyrrolo[2,3-d]pyrimidine scaffold, revealing structural features that elicit antiviral activity. Furthermore, we have demonstrated that 9<i>H</i>-purine or 1<i>H</i>-pyrazolo[3,4-d]pyrimidine...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2021-06-01
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| coleção: | Molecules |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/1420-3049/26/13/3779 |
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