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Human MAIT cells inhibit alloreactive T cell responses and protect against acute graft-versus-host disease

Adoptive transfer of immunoregulatory cells can prevent or ameliorate graft-versus-host disease (GVHD), which remains the main cause of nonrelapse mortality after allogeneic hematopoietic stem cell transplantation. Mucosal-associated invariant T (MAIT) cells were recently associated with tissue repa...

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Principais autores: Nana Talvard-Balland, Marion Lambert, Mathieu F. Chevalier, Norbert Minet, Marion Salou, Marie Tourret, Armelle Bohineust, Idan Milo, Véronique Parietti, Thomas Yvorra, Gérard Socié, Olivier Lantz, Sophie Caillat-Zucman
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical investigation 2024-03-01
Serier:JCI Insight
Fag:
Immunology
Transplantation
Online adgang:https://doi.org/10.1172/jci.insight.166310
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