Treatment with specific and pan-plasma membrane calcium ATPase (PMCA) inhibitors reduces malaria parasite growth in vitro and in vivo

Abstract Background Rapid emergence of Plasmodium resistance to anti-malarial drug mainstays has driven a continual effort to discover novel drugs that target different biochemical pathway (s) during infection. Plasma membrane Calcium + 2 ATPase (PMCA4), a novel plasma membrane protein that regulate...

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Bibliografiska uppgifter

Huvudupphov:	Puji B. S. Asih, Josephine E. Siregar, Farahana K. Dewayanti, Normalita E. Pravitasari, Ismail E. Rozi, Andita F. M. Rizki, Rifqi Risandi, Kevin N. Couper, Delvac Oceandy, Din Syafruddin
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2022-06-01
Serie:	Malaria Journal
Ämnen:	PMCA4 inhibitors Antimalarial activity Plasmodium falciparum Plasmodium berghei Plasmodium yoelii In vitro and in vivo
Länkar:	https://doi.org/10.1186/s12936-022-04228-0
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