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Hemoglobin-based oxygen carriers, oxidative stress and myocardial infarction

IntroductionDevelopment of hemoglobin-based oxygen carriers (HBOCs) for use as temporary blood replacement solutions and treatment of hemorrhagic shock has been hindered because of evidence HBOC infusion increases the risk of myocardial infarction (MI).MethodsTo gain insight into potential toxicity...

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Autor principal: Timothy N. Estep
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-04-01
coleção:Frontiers in Physiology
Assuntos:
hemoglobin-based oxygen carriers
HBOC
myocardial infarction
oxidative stress
nitric oxide
hemoglobin autoxidation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphys.2025.1551932/full
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