Role and targeting of anaplastic lymphoma kinase in cancer

Abstract Anaplastic lymphoma kinase (ALK) gene activation is involved in the carcinogenesis process of several human cancers such as anaplastic large cell lymphoma, lung cancer, inflammatory myofibroblastic tumors and neuroblastoma, as a consequence of fusion with other oncogenes (NPM, EML4, TIM, et...

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Principais autores:	Carminia Maria Della Corte, Giuseppe Viscardi, Raimondo Di Liello, Morena Fasano, Erika Martinelli, Teresa Troiani, Fortunato Ciardiello, Floriana Morgillo
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2018-02-01
Series:	Molecular Cancer
Assuntos:	ALK Crizotinib Alectinib Ceritinib Tyrosine kinase inhibitor Resistance
Acceso en liña:	http://link.springer.com/article/10.1186/s12943-018-0776-2
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