Design, physicochemical characterisation, and in vitro cytotoxicity of cisplatin-loaded PEGylated chitosan injectable nano / sub-micron crystals

The study aimed to develop cisplatin-loaded PEGylated chitosan nanoparticles. The optimal batch of cisplatin-loaded PEGylated chitosan nanoparticles had a + 49.9 mV zeta potential, PDI of 0.347, and % PDI of 58.9. Nanoparticle zeta size was 741.4 z. d.nm, the size in diameter was 866.7 ± 470.5 nm, a...

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Detalhes bibliográficos

Principais autores:	Muhammad H. Sultan, Sivakumar S. Moni, Saad S. Alqahtani, Mohammed Ali Bakkari, Abdulrahman Alshammari, Yosif Almoshari, Saeed Alshahrani, Osama A. Madkhali, Syam Mohan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2023-06-01
coleção:	Saudi Pharmaceutical Journal
Assuntos:	Cancer Cisplatin Nanoparticles Pegylated Chitosan Zetapotential Polydispersity Index
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1319016423000877
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