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Dynamics of gene regulatory networks and their dependence on network topology and quantitative parameters – the case of phage λ

Abstract Background Gene regulatory networks can be modelled in various ways depending on the level of detail required and biological questions addressed. One of the earliest formalisms used for modeling is a Boolean network, although these models cannot describe most temporal aspects of a biologica...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Dace Ruklisa, Alvis Brazma, Karlis Cerans, Thomas Schlitt, Juris Viksna
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2019-05-01
Schriftenreihe:BMC Bioinformatics
Schlagworte:
Gene regulatory networks
Hybrid systems
Phage λ
Stable behaviours
Model validation
Online-Zugang:http://link.springer.com/article/10.1186/s12859-019-2909-z
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