Comparison of a SARS-CoV-2 mRNA booster immunization containing additional antigens to a spike-based mRNA vaccine against Omicron BA.5 infection in hACE2 mice.

The emergence of SARS-CoV-2 variants presents challenges to vaccine effectiveness, underlining the necessity for next-generation vaccines with multiple antigens beyond the spike protein. Here, we investigated a multiantigenic booster containing spike and a chimeric construct composed of nucleoprotei...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Jacklyn R Hurst, Maedeh Naghibosadat, Patrick Budowski, Jun Liu, Philip Samaan, Frans Budiman, Alexandra Kurtesi, Fredo Qi, Haritha Menon, Rajesh Krishnan, Jumai Abioye, Anne-Claude Gingras, Mario Ostrowski, Natalia Martin Orozco, Robert A Kozak
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2024-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	https://doi.org/10.1371/journal.pone.0314061
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!