A Computationally Designed Prefusion Stabilized Human Metapneumovirus Fusion Protein Vaccine Antigen Elicited a Potent Neutralization Response

<b>Background/Objectives:</b> Human metapneumovirus (hMPV) is a leading cause of respiratory infections in the elderly, with high morbidity and mortality and with no vaccines or specific therapies available. The primary protective antigen of hMPV is the fusion protein, and its prefusion conformation...

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Үндсэн зохиолчид:	Michael Kishko, Antonia Stuebler, Sukanya Sasmal, Yvonne Chan, Dean Huang, Christopher Reyes, Jasmine Lin, Owen Price, Ana Kume, Katie Zong, Christine Bricault, Judith Alamares-Sapuay, Linong Zhang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2025-05-01
Цуврал:	Vaccines
Нөхцлүүд:	computational design hMPV subunit vaccine prefusion stabilization
Онлайн хандалт:	https://www.mdpi.com/2076-393X/13/5/523
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!