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User-Friendly Replication-Competent MAdV-1 Vector System with a Cloning Capacity of 3.3 Kilobases

Mouse adenoviruses (MAdV) play important roles in studying host–adenovirus interaction. However, easy-to-use reverse genetics systems are still lacking for MAdV. An infectious plasmid pKRMAV1 was constructed by ligating genomic DNA of wild-type MAdV-1 with a PCR product containing a plasmid backbone...

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Principais autores: Zhichao Zhang, Xiaojuan Guo, Wenzhe Hou, Xiaohui Zou, Yongjin Wang, Shuqing Liu, Zhuozhuang Lu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-05-01
coleção:Viruses
Assuntos:
mouse adenovirus 1
replication competent
vector
packaging capacity
transgene
infectious plasmid
Acesso em linha:https://www.mdpi.com/1999-4915/16/5/761
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