PD-1/PD-L1 Checkpoint Inhibitors in Tumor Immunotherapy

Programmed death protein 1 (PD1) is a common immunosuppressive member on the surface of T cells and plays an imperative part in downregulating the immune system and advancing self-tolerance. Its ligand programmed cell death ligand 1 (PDL1) is overexpressed on the surface of malignant tumor cells, wh...

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Autors principals:	Jinhua Liu, Zichao Chen, Yaqun Li, Wenjie Zhao, JiBiao Wu, Zhen Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-09-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	PD-1 inhibitor PD-L1 inhibitor biomarkers immune checkpoint tumor immune escape immune-related toxicity
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2021.731798/full
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