Attenuated titin protein expression is associated with advanced stages of ovarian cancer

This study explores the role of titin, a giant muscle protein, in the progression of epithelial ovarian cancer (EOC). We examined titin levels in tissues and sera from EOC patients across stages I–IV and in chemoresistant EOC cells. Tissue samples underwent immunohistochemistry, and serum titin leve...

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Autori principali:	Harvey Sharma, Jaskaran Aujla, Asad Nawaz, Thabet Khasawneh, Ayesha Alvero, Robert T. Morris, Asma Basha, Laila Tutunji, Toshima Z. Parris, Khalil Helou, Ghassan M. Saed
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-03-01
Serie:	Molecular Therapy: Oncology
Soggetti:	MT: Regular Issue attenuated titin expression chemoresistance ovarian cancer therapeutic marker titin mutations
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2950329925000013
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