HmmUFOtu: An HMM and phylogenetic placement based ultra-fast taxonomic assignment and OTU picking tool for microbiome amplicon sequencing studies

Abstract Culture-independent analysis of microbial communities frequently relies on amplification and sequencing of the prokaryotic 16S ribosomal RNA gene. Typical analysis pipelines group sequences into operational taxonomic units (OTUs) to infer taxonomic and phylogenetic relationships. Here, we p...

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Detalhes bibliográficos

Principais autores:	Qi Zheng, Casey Bartow-McKenney, Jacquelyn S. Meisel, Elizabeth A. Grice
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-06-01
coleção:	Genome Biology
Assuntos:	Microbiome 16S rRNA gene FM-index HMM profile alignment Phylogenetic placement Taxonomic assignment
Acesso em linha:	http://link.springer.com/article/10.1186/s13059-018-1450-0
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