Mechanisms by which tryptophan metabolites enhance intestinal barrier function to prevent necrotizing enterocolitis in preterm infants

Necrotizing enterocolitis (NEC) is one of the most severe intestinal diseases affecting preterm infants, characterized by high mortality rates and significant long-term complications, which present substantial challenges to clinical management. The primary pathological mechanism underlying NEC is th...

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Detalhes bibliográficos

Principais autores:	Xinxin Cui, Jianli Qiu, Yan Xu, Zhiwei Guan, Ying Ding, Suping Yu, Shuhua Fan, Guihua Song, Xianqing Ren
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-04-01
coleção:	Frontiers in Immunology
Assuntos:	Aryl hydrocarbon receptor (AhR) indole metabolites Necrotizing enterocolitis (NEC) tryptophan metabolism intestinal barrier
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1782006/full
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