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Deubiquitinase JOSD1 tempers hepatic proteotoxicity

Abstract Derangements in protein homeostasis and associated proteotoxicity mark acute, chronic, and drug-induced hepatocellular injury. Metabolic dysfunction-associated proteasomal inhibition and the use of proteasome inhibitors often underlie such pathological hepatic proteotoxicity. In this study,...

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Autori principali: Saheli Chowdhury, Abhishek Sen, Debajyoti Das, Partha Chakrabarti
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2024-09-01
Serie:Cell Death Discovery
Accesso online:https://doi.org/10.1038/s41420-024-02177-y
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