Dynamics simulations of hypoxia inducible factor-1 regulatory network in cancer using formal verification techniques

Hypoxia-inducible factor-1 (HIF-1) regulates cell growth, protein translation, metabolic pathways and therefore, has been advocated as a promising biological target for the therapeutic interventions against cancer. In general, hyperactivation of HIF-1 in cancer has been associated with increases in...

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Prif Awduron:	Hafiz Muhammad Faraz Azhar, Muhammad Tariq Saeed, Ishrat Jabeen
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Frontiers Media S.A. 2024-11-01
Cyfres:	Frontiers in Molecular Biosciences
Pynciau:	hypoxia-inducible factor-1 (HIF-1) vascular endothelial growth factor (VEGF) oglycosylation transferase (OGT) glucose transporter-1 (GLUT-1) extracellular single regulated kinase (ERK) cellular myelocytomatosis oncogene (C-MYC)
Mynediad Ar-lein:	https://www.frontiersin.org/articles/10.3389/fmolb.2024.1386930/full
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