Improving virtual screening of G protein-coupled receptors via ligand-directed modeling.
G protein-coupled receptors (GPCRs) play crucial roles in cell physiology and pathophysiology. There is increasing interest in using structural information for virtual screening (VS) of libraries and for structure-based drug design to identify novel agonist or antagonist leads. However, the sparse a...
Guardado en:
| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2017-11-01
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| Colección: | PLoS Computational Biology |
| Acceso en línea: | http://europepmc.org/articles/PMC5708846?pdf=render |
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