Autoinhibition and relief mechanisms for MICAL monooxygenases in F-actin disassembly
Abstract MICAL proteins represent a unique family of actin regulators crucial for synapse development, membrane trafficking, and cytokinesis. Unlike classical actin regulators, MICALs catalyze the oxidation of specific residues within actin filaments to induce robust filament disassembly. The potent...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2024-08-01
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| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-024-50940-7 |
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