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Epigenetics and chromatin structure regulate var2csa expression and the placental-binding phenotype in Plasmodium falciparum

Plasmodium falciparum is responsible for what appears to be a never-ending public health issue in the developing world. With repeated infections, a gradual semi-immunity to severe malaria can be acquired, but this is disrupted when women become pregnant as the parasite cytoadheres in the placenta to...

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Principais autores: Todd Lenz, Madle Sirel, Hannes Hoppe, Sulman Shafeeq, Karine G Le Roch, Ulf Ribacke
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications Ltd 2026-04-01
Series:eLife
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Acceso en liña:https://elifesciences.org/articles/93632
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