Parameter Estimation of Population Pharmacokinetic Models with Stochastic Differential Equations: Implementation of an Estimation Algorithm

Population pharmacokinetic (PPK) models play a pivotal role in quantitative pharmacology study, which are classically analyzed by nonlinear mixed-effects models based on ordinary differential equations. This paper describes the implementation of SDEs in population pharmacokinetic models, where param...

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Detalhes bibliográficos

Principais autores:	Fang-Rong Yan, Ping Zhang, Jun-Lin Liu, Yu-Xi Tao, Xiao Lin, Tao Lu, Jin-Guan Lin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2014-01-01
Colecção:	Journal of Probability and Statistics
Acesso em linha:	http://dx.doi.org/10.1155/2014/836518
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