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Pathologically expanded peripheral CD4+PD‐1+Foxp3− T‐cell subset promotes B‐cell hyperactivity in patients with rheumatoid arthritis

Abstract Background Rheumatoid arthritis (RA) is an autoimmune disease characterized by destructive polyarthritis, and abnormal T–B‐cell interactions may contribute to its pathogenesis. This study aimed to investigate the characteristics and roles of CD4+ programmed death 1 (PD‐1)+Foxp3− T cells in...

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Hauptverfasser: Ziran Bai, Rui Liu, Jiaqing Liu, Cheng Zhang, Zilong Wang, Jingjing Qi, Yawei Tang, Xia Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2024-03-01
Schriftenreihe:Rheumatology & Autoimmunity
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Online-Zugang:https://doi.org/10.1002/rai2.12114
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