An Efficient Synthesis of a Spirocyclic Oxindole Analogue

An efficient, scaleable synthesis approach towards the spirocyclic oxindole analogue 1’-(tert-butoxycarbonyl)-2-oxospiro[indoline-3,4’-piperidine]-5-carboxylic acid (1) is described. The key steps are dianion alkylation and cyclization of ethyl 2- oxindoline-5-carboxylate (4) and demethyla...

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Bibliografske podrobnosti

Principais autores:	A. Mendonca, Hongxing Zhang, Dawei Teng
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2006-09-01
Serija:	Molecules
Teme:	Spirocyclic oxindole dianion alkylation N-demethylation.
Online dostop:	http://www.mdpi.com/1420-3049/11/9/700/
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