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Friedel–Crafts Reaction of Acylsilanes: Highly Chemoselective Synthesis of 1-Hydroxy-bis(indolyl)methanes and 1-Silyl-bis(indolyl)methanes Derivatives

A novel double Friedel–Crafts reaction of acylsilanes in water is described. This strategy enables synthesis of bis(indolyl)methane derivatives with 1-hydroxy or 1-silyl substituents in moderate to high yield. Compared to the 1-silyl-bis(indolyl)methane derivatives from indole substrate, 1-hydroxy-b...

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Váldodahkkit: Qi Li, Xiu-Xia Liang, Wang Zhang, Man-Yi Han
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2023-07-01
Ráidu:Molecules
Fáttát:
Liŋkkat:https://www.mdpi.com/1420-3049/28/15/5685
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