Gender Disparity Impacts on Thymus Aging and LHRH Receptor Antagonist-Induced Thymic Reconstitution Following Chemotherapeutic Damage

One of the main consequences of thymus aging is the decrease in naïve T cell output. This condition accelerates at the onset of puberty, and presents as a major clinical complication for cancer patients who require cytoablative therapy. Specifically, the extensive use of chemotherapeutics, such as c...

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Principais autores:	Michael Ly Hun, Kahlia Wong, Josephine Rahma Gunawan, Abdulaziz Alsharif, Kylie Quinn, Ann P. Chidgey
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-03-01
coleção:	Frontiers in Immunology
Assuntos:	thymus thymic epithelial cell aging gender sex hormone deprivation luteinizing hormone-releasing hormone
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2020.00302/full
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