Endothelial pannexin 1–TRPV4 channel signaling lowers pulmonary arterial pressure in mice

Pannexin 1 (Panx1), an ATP-efflux pathway, has been linked with inflammation in pulmonary capillaries. However, the physiological roles of endothelial Panx1 in the pulmonary vasculature are unknown. Endothelial transient receptor potential vanilloid 4 (TRPV4) channels lower pulmonary artery (PA) con...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Zdravka Daneva, Matteo Ottolini, Yen Lin Chen, Eliska Klimentova, Maniselvan Kuppusamy, Soham A Shah, Richard D Minshall, Cheikh I Seye, Victor E Laubach, Brant E Isakson, Swapnil K Sonkusare
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	eLife Sciences Publications Ltd 2021-09-01
Cyfres:	eLife
Pynciau:	TRP channel Pannexin 1 purinergic signaling Caveolin 1 pulmonary vasculature
Mynediad Ar-lein:	https://elifesciences.org/articles/67777
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