Uncoupling the Trade-Off between Somatic Proteostasis and Reproduction in Caenorhabditis elegans Models of Polyglutamine Diseases

Caenorhabditis elegans somatic protein homeostasis (proteostasis) is actively remodeled at the onset of reproduction. This proteostatic collapse is regulated cell-nonautonomously by signals from the reproductive system that transmit the commitment to reproduction to somatic cells. Here, we asked whe...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Anat Ben-Zvi, Netta Shemesh, Nadav Shai, Lana Meshnik, Rotem Katalan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2017-04-01
coleção:	Frontiers in Molecular Neuroscience
Assuntos:	aging arachidonic acid (AA) Caenorhabditis elegans lipl-4 neurodegenerative diseases proteostasis
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fnmol.2017.00101/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!