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Base Sequence Context Effects on Nucleotide Excision Repair

Nucleotide excision repair (NER) plays a critical role in maintaining the integrity of the genome when damaged by bulky DNA lesions, since inefficient repair can cause mutations and human diseases notably cancer. The structural properties of DNA lesions that determine their relative susceptibilitie...

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Principais autores: Yuqin Cai, Dinshaw J. Patel, Suse Broyde, Nicholas E. Geacintov
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2010-01-01
Serija:Journal of Nucleic Acids
Online dostop:http://dx.doi.org/10.4061/2010/174252
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