Cefiderocol activity against planktonic and biofilm forms of β-lactamase-producing pseudomonas aeruginosa from people with cystic fibrosis

Objectives: Chronic Pseudomonas aeruginosa infections are a leading cause of acute pulmonary exacerbations in people with cystic fibrosis (pwCF). Intrinsic antibiotic resistance and biofilm formation complicate treatment. This study investigates the genomic diversity and cefiderocol efficacy against...

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Principais autores:	Giorgia Fabrizio, Mauro Truglio, Ilaria Cavallo, Francesca Sivori, Massimo Francalancia, Rodolfo J. Riveros Cabral, Manola Comar, Maria Trancassini, Daniele Emanuele Compagnino, Fabiana Diaco, Guido Antonelli, Fiorentina Ascenzioni, Giuseppe Cimino, Fulvia Pimpinelli, Enea Gino Di Domenico
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2025-06-01
Series:	Journal of Global Antimicrobial Resistance
Assuntos:	Cystic fibrosis Pseudomonas aeruginosa Cefiderocol Biofilm Avibactam
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2213716525000827
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