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Cell-Penetrating and Targeted Peptides Delivery Systems as Potential Pharmaceutical Carriers for Enhanced Delivery across the Blood–Brain Barrier (BBB)

Among the challenges to the 21st-century health care industry, one that demands special mention is the transport of drugs/active pharmaceutical agents across the blood–brain barrier (BBB). The epithelial-like tight junctions within the brain capillary endothelium hinder the uptake of most pharmaceut...

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Principais autores: Soma Mondal Ghorai, Auroni Deep, Devanshi Magoo, Chetna Gupta, Nikesh Gupta
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-07-01
Serier:Pharmaceutics
Fag:
cell-penetrating peptides (CPPs)
endosomal entrapment
homing peptides
blood–brain barrier (BBB)
tumour-specific markers
siRNA-CPP delivery
Online adgang:https://www.mdpi.com/1999-4923/15/7/1999
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