The phage-encoded PIT4 protein affects multiple two-component systems of Pseudomonas aeruginosa

ABSTRACT Two-component systems (TCSs) control a large proportion of virulence factors in Pseudomonas aeruginosa. Yet, investigations on inhibitors of regulatory pathways of TCSs remain scarce, despite their potential in anti-virulence strategies. This work elucidates the molecular mechanism of PIT4,...

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Auteurs principaux:	Kaat Schroven, Leena Putzeys, Alison Kerremans, Pieter-Jan Ceyssens, Marta Vallino, Jan Paeshuyse, Farhana Haque, Ahmed Yusuf, Matthias D. Koch, Rob Lavigne
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology 2023-12-01
Collection:	Microbiology Spectrum
Sujets:	bacteriophages TCS HK FleS PilS T4P
Accès en ligne:	https://journals.asm.org/doi/10.1128/spectrum.02372-23
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